Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

San Francisco leaders and community members came together Sunday to continue to fight for safer streets on World Day of ...

San Francisco’s Muni launched its first-ever online merchandise store yesterday, releasing over 30 products with the Muni ...

Forward, a San Francisco health technology company once valued at $1 billion, is shutting down after failing to popularize ...

The San Francisco Giants head into the offseason having missed the postseason in seven of the last eight years.

Three hundred and seventeen pairs of white-painted "ghost shoes" lined up on the steps of San Francisco City Hall Sunday. Each was with a name, every one of them representing someone killed on city ...

Down the stretch against the Seattle Seahawks, San Francisco 49ers star pass rusher Nick Bosa was on the sideline. In the ...

The San Francisco 49ers have had to deal with a significant number of injuries to their star players this season, and after ...

New photos show the sickening moment a California man launched a savage assault on a female Safeway employee in San Francisco ...

A judge has temporarily ordered Oakland International Airport in California to stop using the name "San Francisco Bay Oakland ...

Tyrone Riley IV scored 28 points as San Francisco beat Chicago State 82-37 on Saturday. Riley had three steals for the Dons (4-0). Ryan Beasley scored 10 points while shooting 3 for 6, including 2 for ...

The 49ers won the first meeting in Seattle, 36-24, for their sixth straight victory against the Seahawks, counting their ...