Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

The findings from this study significantly advance our understanding of the unconventional autophagy-mediated secretion of the multifunctional protein PARK7/DJ-1, which is implicated in various ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Abstract: In this paper, we present a simulation and hardware realization on a compact electronic chip of a simplified Growth Hormone secretion mechanism. After realization, the chip is a stand-alone ...

Introduction: The progression to hyperglycaemia in type 2 diabetes is marked by β-cell insulin secretory dysfunction and cell loss. We have previously demonstrated that apolipoprotein (apo) A-I, the ...

Life-forms with no brain are capable of some astounding things. It might sound like sci-fi nightmare fuel, but some bacteria can wage kamikaze chemical warfare. Pathogenic bacteria make us sick by ...

You suddenly feel sick -- pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host's defense mechanisms and ...

The type VI secretion system (T6SS) is a phage-derived contractile nanomachine primarily involved in interbacterial competition. Its pivotal component, TssA, is indispensable for the assembly of the ...

A four-year project aimed at developing whey protein from CO2 and electricity has been selected for investment by the European Commission via its innovation programme. From a pool of more than 440 ...