Researchers discovered that a longevity gene from centenarians can reverse heart damage linked to progeria, suggesting a new approach to treating rapid and age-related heart aging. A major advancement ...
Edited by Andrew Marks, Columbia University College of Physicians and Surgeons, New York, NY; received January 19, 2024; accepted March 21, 2024 Hutchinson–Gilford progeria syndrome (HGPS) is a rare ...
Unifying global IP rights and enabling up to $5 million in potential shareholder contributions, the agreement strengthens ...
Researchers found a genetic variant in people with especially long lives, which could help children who age prematurely | ...
Despite decades of research, the extent to which human progerias resemble accelerated ageing is still unclear and highly debated. To understand this connection, an ongoing characterization of genetic ...
Two of the best characterized progeroid syndromes are Werner syndrome and Hutchinson–Gilford progeria syndrome (HGPS). The genes targeted for mutation in these diseases (WRN and LMNA, respectively) ...
A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives—over 100 years old. The ...
"The findings highlight miRNA-145-5p and miRNA-27b-3p as potential therapeutic targets to address adipose tissue defects and premature aging in HGPS." BUFFALO, NY — October 7, 2025 — A new research ...
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Deregulated miR-145 and miR-27b impact adipogenesis in Hutchinson-Gilford progeria syndrome
A new research paper was published in Volume 17, Issue 9 of Aging-US on August 27, 2025, titled, "Deregulated miR-145 and miR-27b in Hutchinson-Gilford progeria syndrome: implications for adipogenesis ...
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