Researchers have developed a highly efficient way to produce chiral multi-centered fused tricyclic compounds of which core structure is often found in bioactive compounds including medicines.

A learning module for organic chemistry students; introduce undergrads to the concept of stereochemistry with slide decks and assignments. Topics covered include: chirality, enantiomers, diastereomers ...

After recovering the solid by filtration, the team treats it with ethanol and water to remove BINOL, leaving mostly one isomer of the target chiral ammonium compound (shown).