Monaco are also struggling and welcome Spurs amid a four-game winless streak, though that run includes a 2-2 draw with Manchester City. Monaco vs Tottenham is scheduled for an 8pm BST kick-off on Wednesday, October 22, 2025. The match will take place at Stade Louis II.

Meanwhile, Monaco - set to play their first Champions League game under Sebastien Pocognoli after Adi Hutter's dismissal - have just one point from their opening two games, drawing 2-2 with Manchester City after an opening 4-1 thrashing at the hands of Club Brugge.

In the Champions League in 2016, it was two 2-1 wins for Monaco, though Tottenham did beat them 4-1 in the Europa League the year before. What’s your prediction for this one? Let us know in the comments!

Liverpool face an in-form Aston Villa as the Premier League champions look to arrest their remarkable collapse on Saturday, while Arsenal aim to surge further clear in the title race.Villa have overcome their difficult start with four consecutive wins,

Monaco got thrashed 4-1 by Club Brugge but did manage a draw against Man City in their second Champions League contest. However, Wednesday’s game will take place over a month since Monaco’s last win, and this is a team who’ve won just four of 10 games this season.

Villarreal is in the Champions League for the first time since the 2021-22 season, as the team finished fifth in La Liga last year. Villarreal is looking for its first win, having lost to Tottenham Hotspur and drawn with Juventus. These two teams met in the group stage of the 2011-12 UCL season, with ManCity winning both matches.