A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and ...

A team of Berlin-based researchers led by Jana Kroll and Christian Rosenmund has captured the fleeting moment a nerve cell ...

(1) A nerve impulse arrives. (2) This causes calcium ion channels to open, resulting in an influx of calcium ions in the terminal. (3) This causes synaptic vesicles to fuse with the terminal membrane, ...

Interactions of two voltage-gated calcium channels and a pump enable separate control of exocytosis and endocytosis at chemical synapses. Chemical synapses transmit information within the nervous ...

Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...

Neurotransmission, or synaptic transmission, corresponds to the movement of signals between neurons, permitting the transmission of information through the proliferation of action potentials. This ...

A technology called single-molecule imaging has enabled scientists at the University of Maryland to identify the architecture of synapses – the tiny junctions that connect neurons together – and ...

A recent multi-species study has found that the CD2AP gene, a known risk gene for Alzheimer’s disease, is key for regulating synaptic transmission. A multi-species study integrating experiments in ...

In the nervous system, electrical signals are sent down a nerve cell (neuron) to a synapse that transmit the electrical signal from one nerve cell to another. Their main purpose is to limit the ...

Fifty-plus years ago, Julius Axelrod and his colleagues discovered the phenomenona of neurotransmitter inactivation by reuptake into the nerve terminal, a finding that led to the development of ...