Two clubs look for an important win on Sunday in English Premier League action, as Tottenham Hotspur returns home to face Aston Villa.

Manchester United would show they perhaps really are turning a corner if they can beat Brighton & Hove Albion on Saturday for just the second time in eight league meetings.

Tottenham Hotspur is back on its home pitch on Sunday looking to hang with the English Premier League elite with a contest against Aston Villa.

On the other side, Chelsea is looking to break the schneid the club finds itself in. After picking up points in each of their first four matches of the season, including wins over West Ham and Fulham, the Blues have stumbled, dropping 2-1 results to both Manchester United and Brighton, losing to the Seagulls on home soil last weekend.

Liverpool take on Brentford as Arne Slot aims to translate their superb Champions League win in Frankfurt into Premier League points.

Below we keep you up to date on all of the latest Premier League injury news, with details on who is out, unavailable due to suspension and who is struggling for fitness at all 20 clubs. OUT: Martin Odegaard (knee - MORE ), Kai Havertz (knee - MORE ), Gabriel Jesus (knee), Noni Madueke (knee).

All the latest from the Champions League as Arsenal, Newcastle and Manchester City are in action plus latest team news and news conferences.

Monaco are also struggling and welcome Spurs amid a four-game winless streak, though that run includes a 2-2 draw with Manchester City. Monaco vs Tottenham is scheduled for an 8pm BST kick-off on Wednesday, October 22, 2025. The match will take place at Stade Louis II.

Michael Owen has changed his Premier League title prediction and has revealed exactly who he thinks will be finishing in the top four this term. Arsenal sit top of the table after the opening eight games of the 2025-26 season, looking to land their first top-flight trophy in 22 years.

The 2025-26 Europa League begins this week, as Nottingham Forest and Aston Villa bid to keep the UEFA Cup in the Premier League after Tottenham Hotspur beat Manchester United to the silverware last season.

Liverpool face Premier League penalty after shock rule break vs. Man United originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. could face a fine and reprimand following their 2-1 loss to .