Ohio State vs. Purdue Prediction, Odds, Picks - November 8, 2025

Preview the Nov. 8 matchup between the Ohio State Buckeyes and Purdue Boilermakers with predictions, odds, over/under, spread, betting lines and more.
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Live updates: Ohio State takes on Purdue in penultimate road game of regular season

No. 1 Ohio State puts its 12-game winning streak on the line against a Purdue squad desperate for its first Big Ten victory of the season. The undefeated Buckeyes have won the last three meetings against the Boilermakers,

Ohio State vs. Purdue three and out: Some takeaways from the first half in West Lafayette

Three quick takeaways from the first half in West Lafayette as Ohio State football leads Purdue 24-3 at the break.

No. 2 IU football wrote its origin story for new era, sets up collision course with No. 1 Ohio State

Curt Cignetti has completely flipped the culture of IU football, the win at Penn State the next stamp of approval. Two undefeateds may soon meet, defined differently.

Julian Sayin, Jeremiah Smith propel No. 1 Ohio State past Purdue 34-10 for 13th straight win

Julian Sayin threw for 303 yards and one touchdown and No. 1 Ohio State used four straight scoring drives in the second quarter to pull away from Purdue 34-10.

Ohio State football missing key player in released availability report for Purdue game

Ohio State football released its player availability and injury status report for the Purdue game and a key player will be out Saturday.

As Ohio State beats Purdue with ease, Jeremiah Smith earns Heisman buzz of his own

Carnell Tate was unexpectedly absent, but Jeremiah Smith stole the show in No. 1 Ohio State's 34-10 win at Purdue.

Ohio State football dealt unfortunate injury blow for Purdue clash

Ohio State is going into a game against Purdue on Saturday, without a key offensive lineman. The Buckeyes look to stay undefeated.
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