Little is known about acetylcholine (ACh) modulation of central visual processing in humans. Receptor densities in visual brain regions are differentially distributed suggesting that receptor subtypes ...
This is a preview. Log in through your library . Abstract It is widely appreciated that neurotransmission systems interact in their effects on human cognition, but those interactions have been little ...
Nicotinic and muscarinic ACh receptor agonists and acetylcholinesterase inhibitors (AChEls) can enhance cognitive function. However, it is unknown whether a common signaling pathway is involved in the ...
(Left) Nicotine withdrawal reduces nicotinic receptor activity, leading to a relative increase in muscarinic receptor activity and disrupting acetylcholine signaling balance. (Right) Suppressing ...
The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor–blocking activity but causes cholinergic adverse events. Trospium is a peripherally ...
Shares in Pfizer spinout Cerevel Therapeutics have more than doubled after it reported positive early-stage results with CVL-231, a drug for schizophrenia that it thinks could have a clear side-effect ...
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