In tests on human volunteers, Duke University Medical Center researchers have found that even small amounts of alcohol boost the pleasurable effects of nicotine, inducing people to smoke more when ...

A new in vitro study has revealed that nicotine and cotinine, a metabolite of nicotine, can potentially inhibit DNA damage caused by a certain carcinogen in smoke. The carcinogen 4-(methylnitrosamino) ...

Nicotine addiction remains one of the most persistent global health challenges, yet the cellular mechanisms underlying it are less explored. Now, researchers have discovered that astrocytes, glial ...

CALTECH CHEMISTS have solved the chemical mystery of why nicotine binds to acetylcholine receptors with high affinity in the brain but with low affinity in muscles. Such information will help ...