Researchers have combined cutting-edge cryo-electron microscopy (cryo-EM) with computational molecular modeling to produce a near atomic-resolution model of the interaction between microtubules -- ...

Microtubule motor proteins can be either plus end motors or minus end motors depending on the direction of movement. Mitosis requires the trafficking of proteins along microtubules to produce two ...

A new study by researchers from Drexel University College of Medicine reverses the popular scientific dogma that the protein tau stabilizes microtubules within brain cells. The scientists’ new ...

Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, ...

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide. Microtubule fibres ...

This is a preview. Log in through your library . Abstract Indirect immunofluorescence microscopy was used to survey the three-dimensional distribution of microtubules throughout the cell cycle in the ...

PURPOSE: To analyze the available data concerning mechanisms of action of and mechanisms of resistance to the antitubulin agents, vinca alkaloids and taxanes, and more recently described compounds.

This is a preview. Log in through your library . Abstract The parasitic nematodes, Ascaridia galli and Trichostrongylus colubriformis, were prepared for electron microscopy with fixatives containing ...