Krüppel-like factors (Klf) 4 and 5 are two closely related members of the Klf family, known to play key roles in cell cycle regulation, somatic cell reprogramming and pluripotency. Here we focus on ...

This is a preview. Log in through your library . Abstract Previous work has shown that when chick embryo mesoderm tissue is seeded onto the free, dorsal surface of established sheets of embryonic ...

The presomitic mesoderm then gives rise to a series of somite pairs that are identical in appearance and become the same cell type through differentiation but differ in structure depending on their ...

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, Vol. 248, No. 747 (Dec. 10, 1964), pp. 245-277 (34 pages) The present investigation was undertaken to fill in ...

In animal development, organogenesis is the process by which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. The germ layers in organogenesis differ by three ...

Receptor tyrosine kinases (RTKs) are a large group of integral membrane signaling molecules. Mutations in the RTK anaplastic lymphoma kinase (Alk) protein have been linked with non-Hodgkin lymphoma, ...

How does the “body” take shape? The body of animals is highly complex, containing distinct regions that carry out specific functions. As the body forms during embryogenesis, three germ layers are ...

The difference between childhood and adult cancers rarely comes down to simply age. Most tumors in children differ biologically from their adult counterparts and are typically due to the type of cell ...