Researchers corrected lamin A gene mutations, preventing skeletal and cardiac abnormalities and extending mice lifespans.

Lamin heart disease is a genetic condition that affects the heart’s ability to pump blood and can cause life-threatening abnormal heart rhythms. It is caused by a mutation in the LMNA gene, which is ...

Lamin heart disease is a genetic condition that affects the heart's ability to pump blood and can cause life-threatening abnormal heart rhythms. It is caused by a mutation in the LMNA gene, which is ...

LMNA-related dilated cardiomyopathy (LMNA DCM) is one of the most aggressive forms of DCM, affecting approximately 100,000 individuals in the United States and Europe, who progress rapidly to ...

Hutchinson-Gilford progeria syndrome (HGPS), an extremely rare genetic disorder, arises when a silent point mutation in the gene encoding the nuclear envelope protein lamin A, LMNA, leads to abnormal ...