WE have observed that repeated injections of reserpine induce atrophy of the thymus in adult and new-born rats (unpublished results). Since the thymus is known to play an important part in immune ...

Mutant mice treated with tamoxifen showed total or near-total regeneration of their youthful thymus, while control mice also given tamoxifen showed predictable thymus function for their age. This held ...

Researchers found a way to boost aging immune systems by turning the liver into a temporary source of immune support signals ...

Immune function deteriorates with age because, in part, the thymus involutes, dramatically decreasing its immune cell output. New evidence indicates that in mice, thymic involution is caused by a ...

Researchers have used an experimental mRNA therapy to make old immune cells in mice behave as if they were young again, ...

Age-related thymic involution causes a decreased output of thymocytes from the thymus, thereby resulting in impairment of T cell-mediated immunity. While alterations in the T cell and ...

In the early 1900s, a strange disease was killing thousands of infants. Termed "status lymphaticus", it was blamed on the thymus, a small, grayish-pink gland weighing no more than 37 grams nestled ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...

As the immune system weakens with age, scientists have found a way to restore some of its lost strength. By delivering mRNA ...

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM* institute, and the Broad Institute have demonstrated that ...

The deterioration in immune function that occurs as an individual ages is thought to occur because the thymus involutes with age, causing a dramatic decrease in T cell output. New data generated by ...