Intrathecal chemotherapy is a form of cancer treatment in which a healthcare professional injects chemotherapy drugs into the cerebrospinal fluid (CSF). This colorless fluid surrounds the brain and ...

Chemotherapy medications can come in many forms and types (oral, injectable, inhaled, etc.). If you need medication, the type that’s right for you will depend on how the medication works and the ...

Panelists discuss how intrathecal delivery of onasemnogene abeparvovec in the STEER study demonstrates statistically significant motor function improvements in older patients with SMA (ages 2-18 years ...

A pair of clinical data sets gives Novartis confidence in a new formulation of the company’s gene therapy Zolgensma for the treatment of older patients with spinal muscular atrophy (SMA). Among SMA ...

Panelists discuss how emerging intrathecal gene therapy for older patients with spinal muscular atrophy (SMA) shows modest efficacy with fewer systemic adverse effects than intravenous administration, ...

More than three years after Novartis’ plan for a speedy approval for intrathecal Zolgensma was thwarted by an FDA requirement for a pivotal phase 3 trial, the company is back with a positive readout ...

Baclofen (Gablofen, Lioresal, Ozobax) is a medication that treats stiff muscles and spasms, a condition called spasticity, that can happen to people with multiple sclerosis (MS) and other nerve ...

Intrathecal baclofen pumps treat lower-limb spasticity, and are mainly used for people with multiple sclerosis, cerebral palsy, or spinal cord injury1 Intrathecal baclofen (ITB) pumps implanted in the ...

Baclofen 50mcg/mL, 500mcg/mL, 2000mcg/mL; for intrathecal inj; preservative-free. <4yrs: not established. ≥4yrs: Give test dose 1 st by intrathecal inj via spinal catheter or lumbar puncture (see full ...

Sometimes cancer cells are able to cross into the fluid that surrounds and protects your brain and spinal cord. Cancer drugs you take by mouth or through a vein can’t get through as easily.