This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...

Research headed by teams at the University of Rochester Center for Translational Medicine and the University of Copenhagen describes for the first time how a spreading wave of disruption and the flow ...

Problems with the brain's waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the ...

Researchers have discovered, in rodents, that fluid that circulates through the brain flows to areas critical for normal brain development and function, suggesting that disruptions to its circulation ...

A newfound "protective shield" in the brain helps clear waste from the organ and serves as a sentry tower for watchful immune cells that monitor for signs of infection, scientists reported in a study ...

The blood-brain barrier prevents xenobiotics from entering the central nervous system. Growing evidence indicates that neurotoxins, such as tributyltin, manganese and nanoparticles, may disrupt the ...

Extra-axial cerebrospinal fluid (EA-CSF) and perivascular space (PVS) segmentation on 24-month scan of a child who was diagnosed with autism. Throughout the day and night, cerebrospinal fluid (CSF) ...