Cells can’t operate without the power supplied by working mitochondria. When the mechanisms that replicate or repair mitochondrial DNA (mtDNA) fail, it can cause a wide range of syndromes for which ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical motion ...

Engineered enzymes are poised to have transformative impacts across applications in energy, materials, biotechnology, and medicine. Recently, machine learning has emerged as a useful tool for enzyme ...

A subtle flaw in a single brain enzyme now looks like one of the earliest sparks that can set dementia in motion. Instead of a slow, mysterious slide into memory loss, researchers are tracing a direct ...

A platform to engineer enzymes responsible for the formation of amide bonds as an effort toward developing biocatalysts for green chemistry. Amide bonds — a type of chemical bond formed between a ...

Researchers at the Manchester Institute of Biotechnology (MIB) have demonstrated how genetically engineered enzymes can harness visible light to drive highly selective chemical reactions. This ...

A newly discovered molecule may hold the key to rebalancing the immune system in lupus and autoimmune diseases. A newly discovered molecule may hold the key to rebalancing the immune system in lupus ...

Small molecule drugs dominate new drug approvals and are crucial for treating diverse diseases. They are typically low-weight, providing easy absorption and versatile delivery methods. Their simpler ...