Aconsortium of 17 laboratories worldwide has presented results contradicting a highly cited study that described a technique to create conditional knockout mice using CRISPR. The preprint, published ...
Adecade-long war over genetically modified mice still rages. In 1994, Klaus Rajewsky's laboratory at the University of Cologne in Germany created the first transgenic conditional knockout mouse. 1 ...
(A) PCR was used to identify wild-type (WT) and VDR knockout homozygous mice. (B) Immunohistochemistry was employed to assess VDR expression in both WT and VDR knockout (KO) homozygous mice. (C) ...