When will Brandon Aiyuk return and play? Will Brandon Aiyuk be back again this season? Read the latest Brandon Aiyuk injury ...

Coach Kyle Shanahan said Monday that the 49ers don't intend to open Aiyuk 's (knee) practice window this week, Nick Wagoner of ESPN.com reports.

Case in point: the latest discourse from 49ers insiders Tim Kawakami and Matt Barrows on San Francisco's star wideout, ...

San Francisco 49ers wide receiver Brandon Aiyuk (knee) still hasn't played a single snap of football in 2025 after suffering ...

The 49ers have yet to open the practice window for Brandon Aiyuk to return, which should start to set in a harsh reality.

It’s a 21-day practice window, so when it opens, that doesn’t necessarily mean he will practice immediately. All that means is that he can return to practice within the 21-day allotment. The 49ers ...

The star wideout had been very visible during practice throughout training camp and early this season, running alongside his fellow receivers during the open portion of practice, with his speed and ...

Ahead of the season, there wasn’t a firm timeline for Aiyuk, with head coach Kyle Shanahan throwing out Week 10 as a ...

The 49ers could desperately use all hands on deck with the number of injuries they have had, but Brandon Aiyuk does not seem like someone they can depend on. It does not appear Aiyuk will make his ...

The 49ers are rolling even with a depleted roster, but could one of their injured stars be back in the mix for San Francisco's second-half surge? General manager John Lynch provided an encouraging ...