Garetosmab is a fully-human monoclonal antibody designed to bind and neutralize Activin A, a major promoter of HO in patients with FOP.

Based on these data and the safety profile, the Independent Data Monitoring Committee (IDMC) recommended those receiving placebo be transitioned to garetosmab as soon as possible; U.S. regulatory ...

Now a new study in Nature led by Harvard scientists reveals two key genetic shifts that remodeled the pelvis to help human ancestors become the upright bipeds ...

H umans are the only primates that walk on two legs. Scientists believe that their uniquely shaped pelvis, the bones that connect the spine to the legs, makes this possible. However, researchers ...

Heterotopic ossification happens when bone grows outside of its normal location and into the surrounding soft tissues of your body. When this happens, the pieces of bone that develop are called ...

Bone regeneration research has taken a significant leap forward with the discovery of a crucial mechanism that could transform treatments for bone disorders. Scientists have identified how Discoidin ...

June 21, 2023 – For patients undergoing surgery for elbow trauma, treatment with the hemostatic drug tranexamic acid (TXA) is associated with a decreased incidence of heterotopic ossification (HO) – a ...

According to the researchers, their conclusions about the facial development of embryonic mice also appears to apply to us humans. "In human fetal development, a temporary upper jawbone (incisivum) ...