Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Gene expression, the intricate process by which cells selectively activate genes to produce proteins, is crucial for cellular ...

What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...

Novel approach designed to address dysregulated RNA splicing events that drive tumor growth and disease progression across ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for ...

The immune system's gradual decline with age, known as immune aging, increases susceptibility to infections, autoimmune diseases, and cancers. T cells, crucial for adaptive immunity, undergo ...

Computational biologists have uncovered how RNA splicing -- a crucial process for isoform expression and protein diversity -- is regulated across different cell types in the peripheral blood. This ...

In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...

Computational biologists from the National University of Singapore (NUS) have uncovered how RNA splicing – a crucial process for isoform expression and protein diversity - is regulated across ...