This ADME 101 video discusses how compounds can become trapped by lysosomes, which can lead to high organ-to-blood ratios and mistaken for active drug transport, how concomitant administration of ...

Experts discuss factors that can affect the outcome of an ADME study, signs that a drug compound shows promise, red flags, and key parameters to determine safety and efficacy. Absorption, distribution ...

Drug absorption, distribution, metabolism and elimination (ADME)-related genes are genes related to the absorption, distribution, metabolism and elimination of drugs. They can be classified into four ...

Pharmacokinetics is the term used to describe the movement of a drug into, through and out of the body. The kinetics of a drug can be split into four phases – absorption, distribution, metabolism, ...

Discover how in silico tools can be used can be used with organ-on-a-chip for the advancement of ADME studies.

The in vitro assays from CN-Bio are effective in predicting clinical outcomes. High-functioning, metabolically competent human single- and multi-organ models are used in studies on drug metabolism, ...

DUBLIN--(BUSINESS WIRE)--The "ADME-Toxicology Testing: Global Strategic Business Report" report has been added to ResearchAndMarkets.com's offering. Global ADME-Toxicology Testing Market to Reach ...

It may sound harsh, but drug candidates that are bound to be poor performers should be identified sooner rather than later—and ruthlessly eliminated from development. Granted, early in development, ...

Expression quantitative trait loci (eQTL) analysis is a powerful approach toward identifying genetic loci associated with quantitative changes in gene expression. We applied genome-wide association ...