Growth cones at the tips of nascent and regenerating axons direct axon elongation. Netrin-1, a secreted molecule that promotes axon outgrowth and regulates axon pathfinding, elevates cyclic AMP (cAMP) ...

We found a Japanese family with hyperthyroidism without autoantibody. DNA sequence analysis of TSHR was undertaken in this family. The functional consequences for the Gs-adenylyl cyclase and ...

A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme ...

Researchers have elucidated an important part of a signal pathway that transmits information through the cell membrane into the interior of a cell. This signal pathway is of great significance for all ...

My laboratory conducts molecular genetic and chemical genetic research using the fission yeast Schizosaccharomyces pombe. Initially, we studied how extracellular glucose triggers repression of ...